How can infertility arise in a male with cancer?

Male infertility can also arise due to cancer—it is different than erectile dysfunction. Men with cancer often present with low testosterone—oftentimes their cancer is associated with an immune system response, and that immune system response can not only be directed against the cancer, but can also, in a non-specific way, negatively affect developing sperm, leading to the death of sperm, with lower numbers of sperm, lower percentages of sperm with normal movement patterns, and as a result, these things can collectively set the stage for a man with cancer to have trouble trying to achieve a pregnancy.